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What are you doing it for? Game design? Movies/CGI? Do you intend to pay for the software? Are you doing this for a uni course or just as a hobby?
If it's just a hobby or bit of fun, Cinema 4D is easiest to get good results from and most fun to use. Cinema 4D is a bit limited though, so If you want to do it professionally you should think about using others. I think the industry standards for game design is 3DSMax, and Maya for movies (though you can use either really, it doesn't make much of a difference and are both made by the same company).
If you need it free, then you're stuck with blender; which in my experience is an absolute chore to use.
I haven't used any of it in 4-5 years though, so my opinions are probably a bit dated (though probably not by much, things move a bit slow in these industries). Also look into Z-Brush.