Brandon Draws weird, seemingly unconnected strips. He's good at it, though.
http://www.drawbrandondraw.com

http://www.threewordphrase.com

KC Green is pretty well known.
He does http://gunshowcomic.com/
And has a personal site: http://kcgreendotcom.com/CC/comics/

Nedroid does comics about Beartato and his friend Reginald. They're all great. Read them.
http://nedroid.com

Superpoop used to be great, but now it's dead.
http://www.superpoop.com

Kate Beaton is Canadian. She does comics about history and literature. They own. http://www.harkavagrant.com

Trubble Club is this weird, psychedelic strip. I love it, though. http://blog.trubbleclub.com/

This Serious is a strip about a Charmander and a Squirtle. They have adventures together. Yes.
http://eyepatch.fireball20xl.com/thisserious

Jordan Crane does 50's inspired surreal comics.
http://whatthingsdo.com/comic/one-step-at-a-time/#3587
Do check out the site above, it has a lot of good samples by indie artists.

Lamezone http://lamezone.net

By the same guy, Anarchy Anarchy http://anarchyanarchyanarchy.net/

Natasha Allegri works on this great cartoon called Adventure Time. If you don't know it, you should be ashamed of yourself because you are a bad person. http://normallife.livejournal.com/

Emily Carroll draws literature and video game inspired stuff. She's very good at it. Start with this scary story: http://emcarroll.com/comics/faceallred/01.html
And then check out her blog: http://sockefeller.livejournal.com/

Radical Boy and The World of the Crystals.
I honestly don't know the guy's site.
http://www.webcomicsnation.com/preachertom/radicalboy/series.php?view=archive&chapter=37711

Joshua Simmons does these macabre adult stories, filled with death and perversion.
Start with Cockbone: http://www.joshuahallsimmons.com/cockbone.html
And then check out Batman: http://www.joshuahallsimmons.com/batman.html

I think many of you know James Kochalka. I'm not a fan of his, but here is his (almost) daily strip: http://www.americanelf.com

http://lr-comic.com

I really don't know what to say about this one. If you like koala bears titfucking men, then I guess it's good. http://thechipperwhale.com

Another collection of good noir-style indie comics.
http://www.murderbookcomic.com/?p=16

http://sally-bloodbath.livejournal.com/

Jesse Moynihan does FORMING and Kime Agine, two very surreal hand-drawn strips. He also started working on Adventure Time recently.
http://jessemoynihan.com

Jordyn Bochon is another Canadian artist (I think).
Start with this: http://www.8et8.net/OT.htm

Dan Hipp mostly does art and design, but he has worked on a few comics as well: http://mrhipp.blogspot.com/

http://buttersafe.com

Tom McHenry is very shrigleyesque. Start with his earlier stuff.
http://noncanon.com

Emmy Cicierega
Start with this: http://b1nd1.deviantart.com/gallery/1826601
And then check out her blog: http://emmycic.livejournal.com

Manly Guys Doing Manly Things: http://thepunchlineismachismo.com

Another comic from What Things Do, by Hellen Jo. Reminded me of Black & White. http://whatthingsdo.com/comic/jin-jam-no-1/#3264

James Harvey is a pervert. Start with this: http://jimbocomics.livejournal.com/437.html#cutid1
And then this: http://jimbocomics.livejournal.com/1612.html#cutid1

The Realist is a strip by the israeli artist Asaf Hanuka. He's quite talented. http://realistcomics.blogspot.com/

Everyone knows Pictures For Sad Children. http://www.picturesforsadchildren.com

And almost everyone knows Romantically Apocalyptic http://www.romanticallyapocalyptic.com/

Luke Pearson rarely updates his blog, but when he does, it's usually something good. http://www.lukepearson.com/

And I'm done!

>>3235 Great stuff. Thanks.

>>3233
I didn't.

Hell I only stumbled in here by acident. And you sir, have made my goddamn day.

>>3200
Awesome thread.

It's been complete for a good while now, But still good.

Concerned : The Half Life & Death Of Gordon Frohman

http://hlcomic.com